Cart
sales@molnova.com
Home - Products - Membrane Transporter/Ion Channel - AMPK - Onjisaponin B

Onjisaponin B

CAS No. 35906-36-6

Onjisaponin B ( —— )

Catalog No. M24315 CAS No. 35906-36-6

Onjisaponin B induces autophagy via the AMPK-mTOR signaling pathway, increases the NGF level and accelerates both the removal of mutant huntingtin and A53T α±-synuclein, it may have potential therapeutic effects on Parkinson disease, Alzheimer disease and Huntington disease.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 140 In Stock
10MG 250 In Stock
25MG 422 In Stock
50MG 620 In Stock
100MG 885 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Group Booking Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    Onjisaponin B
  • Note
    Research use only, not for human use.
  • Brief Description
    Onjisaponin B induces autophagy via the AMPK-mTOR signaling pathway, increases the NGF level and accelerates both the removal of mutant huntingtin and A53T α±-synuclein, it may have potential therapeutic effects on Parkinson disease, Alzheimer disease and Huntington disease.
  • Description
    Onjisaponin B induces autophagy via the AMPK-mTOR signaling pathway, increases the NGF level and accelerates both the removal of mutant huntingtin and A53T α±-synuclein, it may have potential therapeutic effects on Parkinson disease, Alzheimer disease and Huntington disease.
  • Synonyms
    ——
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    AMPK
  • Recptor
    AMPK;Autophagy;mTOR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    35906-36-6
  • Formula Weight
    1573.7
  • Molecular Formula
    C75H112O35
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    OC[C@](C1=CC[C@]2([H])[C@]3(C[C@H](O)[C@@H]4O[C@]([C@@H]([C@@H](O)[C@@H]5O)O)([H])O[C@@H]5CO)C)(CC[C@]6(C(O[C@H](O[C@H](C)[C@H](OC(/C=C/C7=CC=C(OC)C=C7)=O)[C@@H]8O[C@@](O[C@@H](C)[C@H](O)[C@H]9O)([H])[C@@H]9O)[C@@H]8O[C@@](O[C@@H](C)[C@H](O[C@@](OC[C@@H](O[C@]([C@@H]([C@@H](O)[C@H]%10O)O)([H])O[C@@H]%10CO)[C@@H]%11O)([H])[C@@H]%11O)[C@H]%12O)([H])[C@@H]%12O)=O)[C@@]1([H])CC(C)(C)CC6)[C@@]2(CC[C@@]3([H])[C@]4(C)C(O)=O)C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Onjisaponin B derived from Radix Polygalae enhances autophagy and accelerates the degradation of mutant α±-synuclein and huntingtin in PC-12 cells.Int J Mol Sci. 2013 Nov 15;14(11):22618-41.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Tectochrysin

    Tectochrysin leads to apoptotic cell death in NSCLC cells through activation of DR3 and Fas expression via inhibition of STAT3 phosphorylation.

  • Dorsomorphin dihydro...

    Dorsomorphin (BML-275, Compound C) is a potent, selective and reversible AMPK inhibitor with Ki of 109 nM.

  • A-769662

    A small molecule AMPK activator that directly stimulates partially purified rat liver AMPK (EC50=0.8 uM) and inhibits fatty acid synthesis in primary rat hepatocytes (IC50=3.2 uM).

Sign In Join Free